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✨ Glow like you mean it — overnight skin magic in a bottle! ✨
MANYO Bifida Biome Complex Ampoule Serum is a 50ml Korean night serum designed to rejuvenate and repair the skin barrier using a 7-ferment blend and 10 types of hyaluronic acid. Lightweight and fast-absorbing, it delivers multi-layer hydration while protecting skin from environmental damage. Suitable for all skin types, including sensitive and acne-prone skin, it supports a healthy, glowing complexion with daily use.




| ASIN | B08DTTL17D |
| ASIN | B08DTTL17D |
| Active Ingredients | hyaluronic_acid |
| Best Sellers Rank | #19,474 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #438 in Facial Serums |
| Brand Name | ma:nyo |
| Customer Reviews | 4.4 4.4 out of 5 stars (796) |
| Item Form | Drop |
| Item Volume | 50 Milliliters |
| Item Weight | 0.14 Kilograms |
| Manufacturer | Icure |
| Manufacturer | Icure |
| Manufacturer Part Number | 8809730950140 |
| Material Features | Natural |
| Number of Items | 1 |
| Product Benefits | Hydrating |
| Product Dimensions | 1.69 x 1.69 x 4.88 inches; 4.97 ounces |
| Recommended Uses For Product | Hydrating,Nourishing |
| Scent Name | Unscented |
| Skin Type | All |
| Special Ingredients | hyaluronic_acid, probiotics |
| Target Use Body Part | Face |
| Unit Count | 1.7 Fluid Ounces |
J**R
MANYO Bifida Biome Complex is my new favorite serum.
This Bifida Biome Complex in my opinion is even better than EL Advanced Night Repair. In one night this complex has helped texture, pores, over all skin looks better. Go light under the eye, it's a strong serum. Very impressed!
J**I
Great Product
Works well and creates moisturized supple skin. I use it in place of my Lancôme syrum. I use this everyday
P**B
Very pleased
Great product! Absorbs easily, not greasy and can see a difference in fine lines
P**M
Game changer for sensitive skin!!
I have been using this ampoule for the past three months, and I can confidently say it has transformed my skin! As someone with super sensitive, redness-prone combination skin, finding the right product can be a challenge. However, this ampoule has been a game changer. The unique formulation with 10 types of hyaluronic acid provides deep hydration without overwhelming my skin. I’ve noticed a significant reduction in redness and irritation, which has been a huge relief. My skin feels plumper, more elastic, and overall healthier. The texture is lightweight and absorbs quickly, leaving no sticky residue. I love how it layers perfectly under my moisturizer and sunscreen. Plus, the soothing properties have helped calm my sensitive areas, making my skin look more even toned.
K**E
Great for sensitive skin
I bought this because I wanted to try a new serum that was hydrating. I am only giving it four stars because I don’t know exactly if it is this product or other new ones I started using that have transformed my skin over the last month or so. It is very lightweight and has no scent which I love. I have very sensitive and dry skin that is also prone to breakouts. I have not experienced any sensitivity or breakouts from this product. A little goes a long way I literally use one drop across my whole face. My skin tone over the last month has looked so even and bright. When I apply makeup now there is no dry spots and my skin honestly looks and feels fantastic. I think this is a great product to incorporate for those with very sensitive and dry skin.
D**.
Acne safe barrier repair serum
This served as a Tried and trusted barrier repair serum. I can’t attest to the anti aging affects but maybe that’s a long term benefit. I also have acne prone skin and this does not cause breakouts
A**A
Ferments have a place
This is good! This got me into ferments. But serum form is not my favorite delivery system. I like the manyo bifida aqua barrier cream much more. This way I can get a ferment into my routine as the last step. Because using a ferment in the middle of my layering routine forces compromise. I mean it can make your skin sensitive to things that come after. But it can also react to a toner that you might use before. So before you buy, just study what you're going to use it with first.
B**Y
So glowy
I have used this two nights in a row & I Love it !! I used this with the same brand soy milk cleanser & just wow ! I also used the Medicube jelly collagen moisturizer to seal it all in & my skin is glowing & sooo soft ! It’s definitely with the price . I can’t wait to see what results I’ll have in a few weeks.
H**H
Really nice serum and big bottle with 50ml. Most k beauty serums come with 30ml. Sadly I am currently pausing it because I am not sure If I am maybe allergic to fermented ingredients. And yes, this can be a thing. Especially for people with fungal acne or sensitivity to fermented ingredients. Since I tried so much new things recently I am still not sure about that. Besides that fermented skincare is good and beneficial so if you don't have an allergy I recommend using ferments in your routine. Feels great on the skin and doesn't leave a sticky or heavy feeling. I can layer this up to 3 times without issues and I have oily skin. Also important: fermented skincare often needs more time to show results so dont expect to see drastic changes in your skin after a night using it. It should still feel hydrating and nice on the skin :) I will definitely try it out again once my skin calms down and update on the serum. fermented alternatives to this ampoule I know are (in 2024): - Isntree - TW-Real Bifida Ampoule - benton fermentation essence - Numbuzin No. 3 skin softening serum
J**A
One bottle lasts you 8-9 months of daily use, only 1 drop needed. I'm using this for 3 years. It's so good. Girls, get this!!! It's also a dupe for the Estee lauder advanced repair night serum from sephora. It's has everything, peptides, hyaluronic acid, niacinamide, glycerin etc. I LOVE IT!😍😍
M**A
Me encanta este producto, es la segunda vez que lo compro y tengo piel mixta. Me ha ayudado a disminuir arrugas y signos de expresión. También mi piel esta hidratada con glow sin ser grasosa
D**A
It's my second bottle of the serum, been enjoying it so much. Does amazing on the skin and the skin just absorbs it, like its been lacking that moisture 😁
A**A
I really like this serum. It’s a top-quality product, and the price is quite reasonable. The parcel arrived in good condition, with no damage. But I waited almost two weeks for this serum. Although it said ‘standard delivery within 2–4 days’ or something like that, I ended up paying for the order and then received a message saying that delivery would take almost two weeks 🥴
Trustpilot
2 days ago
2 weeks ago