Do I need the base deck to use this expansion, or does it work okay as a stand-alone?

Expansion packs and bundles like this one contain too few cards for a full length game. Smaller expansions and bundles like this one are meant to be additions to the main game—which contains 600 cards.

Do you need the original game, to enjoy this bundle?

We recommend starting your collection with the Cards Against Humanity main game, which contains 600 cards. Smaller expansions and bundles like this one have too few cards for complete game, and are meant to be additions to the main game.

Are any of these cards included in the big black Box?

Assuming you mean the Ultimate Expansion (our carrying case that comes pre-filled with about 2,000 cards), no—none of the packs included in the Nasty Bundle are included.