Does this contain any strains of Soil Based Organisms?

Hyperbiotics PRO-15 strains are lactobacilli and bifidobacteria. They are not soil-based organisms (SBOs), and let us explain why:Lactobacilli and bifidobacteria are resident bacteria in the human GI tract - meaning they colonize and take up residence. SBOs, on the other hand, are transient micro organisms that establish small colonies for brief periods of time and then die off. We should be exposed to SBOs through interactions with soil and even the vegetables we eat. It is true that the commercialization of food has removed much of this contact from our modern lifestyles.However, many adults have an even bigger problem: damaged resident flora (lactobacilli and bifidobacteria). This means that they don't have the proper microbe makeup to interact with soil-based organisms in a healthy and beneficial way. SBOs are spore-forming, they reproduce differently than the beneficial bacteria that are normally part of our flora, and if a person doesn't have healthy colonies of resident bacteria to keep the soil-based organisms in check, the SBOs can proliferate very rapidly, take over the gut and even become pathogenic.Hyperbiotics PRO-15 is focused on repopulating the gut of those who have damaged their resident bacterial makeup through things like the modern diet high in processed and non plant-based foods, exposure to chlorine and antibiotics (either as medicine or in the food supply), and even not being breast-fed as a child.Once you have strong colonies of resident flora and a healthy GI tract, we absolutely recommend increased exposure to SBO's... ideally by interacting more with nature (eating freshly grown, organic fruits and vegetables or even gardening, playing in the dirt or just being outside). If a more nature-based lifestyle isn't an option, SBO supplementation may be a good idea.

Do these need to be refrigerated at all?

No refrigeration is necessary. However, once you open the bottle, you need to store it in a cool, dry place. Really. If you don't live in a cool, dry place, it is best to store your bottle in the fridge or even better, in the freezer, when you can. With PRO-15, there is a guaranteed a shelf life of 18 months after the date of manufacture with zero refrigeration.

What are the probiotic strains in this supplement? i am looking for something specifically that has some B. Infantis.

There are 15 Top Strains formulated in Hyperbiotics PRO-15. Here is an overview of our favorite 8 (including B. Infantis or Bifidobacterium Infantis): L. fermentum - Identified as highly antimicrobial and antioxidative. Helps inhibit the growth of harmful bacteria, yeast and other pathogens and has demonstrated clinical efficacy within immune health. L. acidophilus - Creates a fortress of good colonies that helps keep unwanted organisms out of your gut. Studies show that L. acidophilus helps to reduce occasional diarrhea and enhances your immune system and may help to reduce cholesterol levels. Studies have shown that those taking L. acidophilus experienced significantly more relief from their gastrointestinal discomfort than did those taking a placebo. L. casei - Along with L. Acidolphilus, converts lactose into lactic acid, helping those who are lactose intolerant. Helps to encourage the growth of other beneficial bacteria. B. longum - Assists in breaking down carbohydrates and fighting free radicals. Provides potent antioxidant support and helps to reduce the effects of seasonal allergens. B. lactis - Helps decrease H. pylori and helps the production of the front line cells in your immune system. L. rhamnosus - The leading defense for travelers. Helps reduce occurrences of traveler's diarrhea and food poisoning. L. plantarum - Secretes the oxidant hydrogen peroxide which acts as a weapon to protect your body and must be present for your immune system to function correctly. Creates a healthy barrier in your colon and helps lower luminal pH, creating an unfavorable environment for the growth of pathogens including molds, yeasts and bacteria. B. Infantis - Has been shown to reduce the major symptoms of gastrointestinal disorders, including diarrhea, flatulence, bloating, cramping and constipation. It is particularly popular as a means of combating Irritable Bowel Syndrome (IBS) and has been shown to improve digestion and the body's ability to absorb and process nutrients.

Is this product made in the US?

Yes, it is made in the USA - in Colorado, actually. PRO-15 is also manufactured with two patented technologies: LiveBac Processing and the BIO-tract Delivery System. LiveBac ensures a long shelf life of 18 months after the date of manufacture with zero refrigeration. The second, BIO-tract, is the only controlled-release technology available for probiotics on the market today. With this technology, 15x more of the beneficial flora survive the harsh environment of your stomach acids and reach deep into your intestinal tract alive. These patents are registered in 31 countries (US Patent 8,007,777 and 7,150,623).

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