I know it says to give on an empty stomach, but is it ok to hide the pill in a small piece of food? Not sure my dog would eat just the pill.

Yes! The packaging says “tablets should be given on an empty stomach; however, if needed they can be administered with a small amount of food or treat.” (The reason I took my Sheltie to the vet in the first place was because he suddenly stopped eating. After tests, my dog was prescribed this medication for his liver problems. But how do you feed pills to a dog that won’t eat anything, not even his treats or cheese? Well, the vet opened a can of pate’ CAT FOOD and surprisingly my dog ate it! The vet said cat food is normally too fatty to be healthy for dogs but they’ll eat it -even when they won’t eat anything else-because it’s like a super-juicy hamburger to them! The vet suggested putting the pill in a small ball of canned pate’ cat food, especially if your dog has no appetite. First, give a tiny ball of pate’ without a pill so they anticipate the flavor then give them a ball with the pill hidden in it while showing them there is more- tricking them into gulping down the pill-ball. Follow up with a tiny dab of cat food and you’re done for an hour when they can stop fasting and eat a meal. In my dog’s case, the meal was cat food pate’ for a few days, then soft-ish dog food smeared with cat food pate’, and now we just use the cat food to hide pills in.) Sorry for the long answer, hope it helps someone.

How large are the pills? I have a cat w/ liver failure & the pills from the vet are HUGE. Looking for an alternative asap. Thank You! :)

I give one for my 11 lbs. poodle which is the small one and a larger one for my 22 lbs. poodle. I gave up on the trauma of cramming it down their throat with a pill dispenser. I know direction say on an empty stomach; however, it is important they take the pills so I bought some human liver pate over in the deli meat section and I give the a tiny treat to trick them...about the size of a ballpoint pen end and then I wrap the pill in just enough liver that they wolf it down and then I give them that tiny bit to follow up. I know it sounds crazy but I watched a vet on youtube show how and it worked. The first little bit programs them for the larger piece which only covers the pill...they wolf it right down. I know it is working because the 22lbs. liver was so high it wouldn't even register on the scale. Follow up last week the liver blood work showed a dramatic drop to well below 300. Hope that helps.

Has anyones dog had any adverse reactions to this product? Ours did.

My dog had diarrhea, but it was from a change to raw food, not Denamarin. Once he had transitioned to entirely raw, diarrhea for two days straight. Once he was back on his canned food, he was fine, with normal poop. The real positives are that he has perked up, that he is hungry, and that some of the side effects from Adrenal Cushing's have improved: less water drinking, hair growing in thicker, less of a pot belly, and skin lesions have decreased. I am happy that he is improving and will continue with this.

Nutramax claims this product does not require a persciption (a dietary suppliment) but is only sold to licenseed vets?

No it is not only sold to vets, because my vet told me to go to Amazon to order this product

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Reviews

A**N

Really helped my 14-year old lab

My vet prescribed this for my 14 year old lab who had liver issues, which we discovered after a blood test. The vet said she was otherwise healthy, and could very well live another year if we got the liver stabilized. She gets a one daily pill now, and it has drastically improved her quality of life. You could tell before she was tired, sore, she never ran, struggled to get up some basic stairs and didn't like going for walks... after a few days on this, she was wagging her tail again, and even running and jumping which I hadn't seen her do in probably a year. She'll walk a mile or more with us now and seems happy, head up and tail wagging the entire time. It's made a big difference for her quality of life in her elder years.

17.12.2025

A**R

Liver enzymes back to normal

Helps my senior dogs’ liver enzymes. All 3 were elevated and now back in the normal range! A bit expensive but works to keep my girl healthy

30.12.2025

R**S

it helps

helped keep my liver failure 13 year old dog around another year

1.01.2026

C**R

Vet recommended, good quality, priced right

I'm only giving it four stars for now because I'm so happy my dog will even eat these! (I do need to wrap them in a slice of turkey but I'll do anything to get medicine in him!). His doctor said to try these for a month because his liver enzymes were high, so I can't say "they work" or anything like that because we still have two weeks to go. They seem to be well tolerated - no side effects that are obvious. The price was less than I expected when the doctor told me to order them. (It seems every time there is a new vitamin or medicine, it's almost $100+ !!). Fingers crossed!

11.09.2025

J**R

Great product

Great product ! Cheaper on Snaxin than at the vet!

13.01.2026

S**D

Nutramax Denamarin

Our veterinarian recommended my elderly dog take Denamarin as a supplement. She takes it on an empty stomach daily and seems to be doing very well. For my own convenience, I place a pill inside of a pill pocket and she thinks she’s getting a treat and that way I’m not stressing and neither is she about chewing a pill. The price was outrageous at the vet’s office, so I looked on Amazon and Voila, this is where I will purchase it from now on.

14.11.2025

O**E

Works well

My dog is allergic to the sillimartin .but it did help his liver

8.12.2025

E**S

Cheaper at the vet for the quantity.

I can get it at the Vet for Large Dogs, one tablet instead of 2 capsules a day. For the price, it wasn't worth it.

9.12.2025

Active Ingredients	S-Adenosylmethionine 425 mg, Silybin-phosphatidylcholine complex (SPC)* 120 mg, Providing 35 mg of Silybin A+B Active Ingredients S-Adenosylmethionine 425 mg, Silybin-phosphatidylcholine complex (SPC) 120 mg, *Providing 35 mg of Silybin A+B See more
Brand	Nutramax Laboratories
Customer Reviews	4.6 out of 5 stars 1,259 Reviews
Flavor	Liver
Item Form	Tablet
Item Volume	0.06 Kilograms
Product Benefits	Antioxidant, Digestive Health, Joint Health

Nutramax Laboratories Denamarin Liver Health Supplement for Large Dogs - With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets(Pack of 1)

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