

🍼 Keep your baby’s skin happy and rash-free—because every diaper change deserves the best!
Desitin Daily Defense Baby Diaper Rash Cream features a potent 13% zinc oxide formula that instantly forms a protective barrier to treat, soothe, and prevent diaper rash. Hypoallergenic and free from parabens, phthalates, and dyes, it’s gentle enough for daily use on sensitive baby skin. Trusted by pediatricians and parents, this 4 oz cream seals out wetness from the first application, providing clinically proven relief with a smooth, easy-to-apply texture.
















| ASIN | B00M0N9J20 |
| Active Ingredients | Active Ingredient: Zinc Oxide 13% |
| Age Range (Description) | Baby |
| Age Range Description | Baby |
| Best Sellers Rank | #256 in Baby ( See Top 100 in Baby ) #12 in Diaper Creams |
| Brand | Desitin |
| Brand Name | Desitin |
| Customer Reviews | 4.9 out of 5 stars 3,914 Reviews |
| Global Trade Identification Number | 00074300003016 |
| Item Form | Cream |
| Item Height | 6.2 inches |
| Item Volume | 4 Fluid Ounces |
| Item Weight | 4 Ounces |
| Manufacturer | Kenvue |
| Material Type Free | Paraben Free, Dye Free, Fragrance Free |
| UPC | 074300003016 |
| Unit Count | 4.0 Ounce |
S**I
Best Diaper Cream
Best diaper cream I've used. Not too sticky and not oily at all. Easy to spread and wash off unlike some other brands, but protects the skin well. Will keep buying this when we need more. Our search is done.
P**S
The magical diaper cream
I love desitin , best diaper rash cream hands down . My baby had the the worst diaper rash ever at about 3 weeks old and I started with the purple desitin (maximum strength) and it cleared it up so fast and brought his skin back to normal then I stopped and started using this one and it works wonder it is easy to wipe off unlike the purple one but both are good .I haven't seen my son with a rash since I've been using desitin
D**B
helped heal a rash on leg
great help for a rash in the crease of leg
K**.
Destin! Great
Love Destin! Use it all the time. Amazon made it super easy to have it sent and shipped whenever I need a refill.
A**F
great
So, I’ve been using this cream for a week now, in combination with two moisturizers, and it’s working greatly. Over a year ago, I pretty much ruined my skin. It became extremely rough, dry, thickened, irritated, etc from accidentally using a product with an exfoliant too often. I’ve tried so many things to repair my skin, but nothing has worked. I’m always being told to just use a cream and layer an ointment over it. This never worked for me. Even the thickest ointments seem to dry out and spread everywhere but the spot I need it on. A little over a week ago, I decided to try using this product as my occlusive rather than an ointment, and the results have been amazing. What I do is shower, massage a mixture of cream and ointment into my skin, and apply a layer of this over it after it’s sat on my skin for a minute. After this, I just reapply once or twice as needed. Don’t wash it off until your next shower, just smooth more on too keep a strong barrier so you’re preventing moisture loss. This has worked better than any traditional occlusive method I’ve ever used. This Desitin Zinc Oxide Cream is smooth when applying on the skin, feels lightweight and comfortable, but sticks to the skin, and forms a FAR superior barrier than a petroleum ointment such as Cerave, Aquaphor, or Vasoline. As a result, this product really helps deliver other topical products into your skin, as any good occlusive emollient should. Plus. Zinc Oxide is great for healing skin. I’ve had long time skin cracks that have healed in just a few days. While it’s a great product for diaper rash, it’s ability at helping to restore your moisture barrier, when used in combination with a moisturizer, is highly underrated. I would highly recommend trying it if you have stubborn rough, dry, cracked, irritated, thick skin that just won’t heal.
K**S
This is a great product that actually does what it states.
I developed a bed sore, within 4 days my sore was gone.
D**S
Worth it
Works as described
S**S
Desitin is my go to for rash
I love desitin for a diaper rash - and that was a great deal on it.
Trustpilot
1 month ago
2 weeks ago